IMAGING BONE METASTASIS OF PROSTATE CANCER: A MINI REVIEW

Abstract

Sixty four years old male presented with history of urinary symptoms and raised PSA level (123 ng/ml). Sextant biopsy of prostate revealed adenocarcioma with a Gleason’s score of 8/10. Pelvic MRI revealed grossly enlarged prostate with a hypointense nodule over apex with evidence of right pelvic lymphadenopathy. A radionuclide bone scan (BS) was performed which revealed foci of abnormal tracer deposits over body of sternum with non-specific widespread degenerative arthritic changes (Fig.1). A follow up computerized tomogram (CT) scan (bone window) of chest was unremarkable (Fig.2). Subsequent magnetic resonance imaging (MRI) of sternum revealed two areas of abnormal signal intensity involving body of sternum with post-contrast enhancement consistent with bone metastases (Fig.3). In view of this interesting case, we will elucidate upon the imaging of bone metastasis in patients with prostate cancer (PC).