Correlation of Gated SPECT with Attenuation Corrected and Non-attenuation corrected Myocardial Perfusion Scans

Abstract

Purpose: To find the correlation of Gated Single Photon Emission Tomography (SPECT) with attenuation corrected and non-attenuation myocardial perfusion scan.  Methods: 102 patients referred for Myocardial Perfusion Imaging (MPI); mean age: 54.6 ± 12.6, were enrolled. They all underwent Stress (dynamic or pharmaceutical) and rest Tc-99m Sestamibi studies. The segmental division of left ventricle for gated and perfusion scan was done into seven myocardial regions. Correlation of non-corrected (NC) and attenuation corrected (AC) perfusion images was done with wall motion / thickening of gated SPECT. Results:  Data of 11 patients were discarded due to severe motion artifacts and / or misregistration between CT and SPECT images. Kappa value of 0.22 and 0.59 were noted when correlation between non-attenuation corrected and attenuation corrected myocardial perfusion scans and myocardial wall motions were done respectively. Conclusion: This study demonstrates that Attenuation corrected myocardial perfusion scan has moderate correlation with Gated SPECT as compared to non-attenuation corrected cardiac scan.

Keywords: Myocardial perfusion imaging, Gated SPECT, Attenuation correction.